Clinical resistance to the Bcr-Abl inhibitor imatinib is a critical problem in treating CML. This study investigated the antitumor effect and mechanism of MPT0B169, a new antitubulin agent, in K562 CML cells and their derived imatinib-resistant cells, IMR2 and IMR3.

Open only in winter, La Cave has a rôtisserie where you can dine and dance by the fireplace.

Grinder, winsome grinsome Grinder!

We were Christians; Christians living in a state of undivorce.yet striving to keep the marriage together while living in great unpeace and disharmony.