This has been known for centuries, but it was only twenty years ago that the site of the biological clock (or, as chronobiologists usually call it, our circadian pacemaker) was identified.

In war-time, self-sacrifice would be the obvious appropriate antidote to this depression, and some such mechanism is clearly at work in, for example, Vera Brittain's self-flagellatory dedication to her voluntary nursing, ...

Metrazur, in Grand Central Terminal, throws in a free miniature suitcase with its pretheater meal, filled with cookies to munch on during intermission and a $3 MetroCard for the commute to Broadway.

Although the New England settlers made their commonwealth much less like Old England than Virginia was intended to be, it is important to re-emphasize that the vast majority were not separatists but Puritans.