While hunter–gatherers had lived in a relatively peaceful relationship with microorganisms, by keeping their own numbers at a level the local environment could sustain, the Neolithic farmers created conditions that would eventually let humans experience and maintain crowd diseases.

He started out with the rather obvious alternative of talking to Junior; Hesh’s scheme was more imaginative; and Tony’s idea of torching the restaurant really is out of the box.

But she also describes being boatbound the whole time as constraining: […]

Because そう is a な-adjective, its negative form is そうじゃない, except that そうにない should be used for verbs.