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As our AgNP suppression studies were done at 4-hr time points, these data strongly indicate that the observed AgNP-mediated suppression of M.tb-induced MDM responses resulted from interferences of AgNP with M.tb-induced host cell signaling pathways and not from direct mycobacteriocidal effects of the AgNP. AgNO 3 used as a positive control for M.tb killing (see Material and Methods ) completely abrogated M.tb growth.
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In her investigations on the viroses of tobacco and potato and on cucumber mosaic in solanaceous hosts, Hoggan showed that the presence or absence of vacuolate bodies , and in some cases the combined presence of vacuolate bodies and striate material have undoubted value for the identification of certain viroses.
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