English Dictionary

sirtinol

noun

(organic chemistry) The substituted benzamide 2-[(2-hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, that is biochemically active

Sirtinol is a potent inhibitor of histone deacetylases.

意味（1）

(organic chemistry) The substituted benzamide 2-[(2-hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, that is biochemically active

The present results also showed elevated intracellular Aβ1–42 levels were markedly inhibited by cilostazol and that this inhibition was blocked by KT5720 and sirtinol, indicating that cAMP-dependent protein kinase and SIRT1 underlie the action mechanism of cilostazol, as has been previously reported by Lee et al.