English Dictionary

vesamicol

noun

(organic chemistry, medicine) The drug 2-(4-phenyl-1-piperidyl)cyclohexan-1-ol that inhibits acetylcholine

Vesamicol is a compound used in organic chemistry.

意味（1）

(organic chemistry, medicine) The drug 2-(4-phenyl-1-piperidyl)cyclohexan-1-ol that inhibits acetylcholine

Because synapse loss and dysfunction occur before fibrillary tau tangles emerge in the tauopathy mouse AD model[20 ], VAChT may be used as a possible in vivo target for diagnoses of AD. It has been shown that vesamicol (2-(4-phenylpiperidino) cyclohexanol) binds to the ACh transporter on presynaptic acetylcholine storage vesicles and inhibits ACh uptake into the vesicle[21 ,22 ].