harm from the repercussions of bird droppings on an environment

area, district, particular geographic region

serious, deep, heavy (topic), profound (change), weighty (matter)

seriousness

harm, damage, injury

question, problem on homework etc. / a question; a matter (of time etc.) / a problem (something that needs to be dealt with); a trouble / an issue; a matter

(そこなう) damage, harm, injure / (あやめる) kill / (わざわい) disaster

(swear word) shit, crap

droppings, dung

crappy, for shit: a derogatory emphasizing suffix.