He apologized to soften her anger.

The headache is so severe that I can't concentrate on my work.

It is said that this medicine has mystical properties.

He always replies instantly to messages, so he is very reliable.

His business achieved great success.

Isao is my best friend.

This medicine relieves pain immediately.

The success of this project largely depends on the arbitrariness of each member.

I took a painkiller because I had a severe headache.

I am taking medicine for a cold.