use one thing for many purposes / work someone hard

to use one's head

(archaic, dialect) “isn't it?” / (archaic, dialect) expresses uncertainty or indefiniteness

(informal, colloquial, slang) not do

槍: spear

stem or continuative form of やる (yaru) [godan]

薬科: pharmacy

(informal) Contraction of 嫌になる (iya ni naru).

(slang) to make a どや顔 (doyagao) facial expression

to be done in by / to suffer damage; to be had