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extreme regret
He felt that his failure was the height of extreme regret.
eye pain; eye-ache; ophthalmalgia
My eye pain is so severe that it's hard for me to look at the computer screen.
pain; sensation of pain
Because his sense of pain is dull, he doesn't notice right away when he gets injured.
common use
This word is not only used in Japan, but also common around the world.
analgesia
This medicine has an analgesic effect.
deep regret
His death was a deep regret for all of us.
to lament
He deeply lamented his failure.
smooth; prosperous
His business is going smoothly.
(transitive) to notify / (intransitive) to be skilled
I notified him of the party schedule.
notice / skill
A notice came, so tomorrow's meeting has been cancelled.
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