big, large, great

physically painful, agonizing / difficult, strenuous, mentally trying / mentally agonizing / tight (budget etc.), straitened / forced

no problem; no objection; it doesn't matter

bismuth

he / distal demonstrative, something far off removed from both speaker and listener: that / boyfriend

distal demonstrative, something far off removed from both speaker and listener: that, yon / particularly, male personal third person pronoun: he / by extension from he: boyfriend

he; boyfriend

延期: postponement / 塩基: base (chem.)

エム: katakana notation of the alphabetic letter,"M" or "m"; medium

笑む: to smile; to bloom