As a result of many years of smoking, he developed emphysema.

He is suffering from a serious sickness.

He is ill with a severe cold.

He has been working as a doctor in this town for many years.

I haven't seen him for a long time.

He has been working as a doctor in this town for many years.

The results of the exam are out.

Years of effort finally bore fruit.

Smoking is prohibited in this restaurant.

He smokes every day.