They (referring to women or girls) are my best friends.

He is playing outside.

In addition to keys and wallets, there are many small items in my bag to take outside.

He is playing outside.

He is playing outside the house.

He is deeply interested in Buddhist teachings, but he is open to learning non-Buddhist teachings as well.

It's better for him not to know the truth. After all, ignorance is bliss.

He is feigning ignorance about that problem.

He knows that pain through his own experience.

I have no way of knowing what he is thinking.