(intransitive) (in reaction to something not going as expected) to worry, to be bothered, to be emotionally distressed, to dwell on, to be vexed

to vex, to cause distress: see modern 悩(なや)める (nayameru)

(transitive) to vex, to annoy, to cause distress, to make someone suffer / (intransitive, rare) to be vexed, to be bothered about something, to be distressed about something

the adnominal or attributive form of stative / resultative 悩めり (nayameri, “has been vexed”)