osteoporosis

the adnominal or attributive form of stative / resultative 悩めり (nayameri, “has been vexed”)

(transitive) to vex, to annoy, to cause distress, to make someone suffer / (intransitive, rare) to be vexed, to be bothered about something, to be distressed about something

to vex, to cause distress: see modern 悩(なや)める (nayameru)

(intransitive) (in reaction to something not going as expected) to worry, to be bothered, to be emotionally distressed, to dwell on, to be vexed

grandmother

(chiefly women's speech) first person singular pronoun: I, me

private; mine

(polite) first-person singular pronoun: I, me

a personal or private matter / (by extension) selfishness