(education) Initialism of in-school suspension.

(space science) Initialism of International Space Station.

plural of is

plural of ISS

plural of Isse

A surname from Somali.

(military, obsolete) A movement of soldiers towards an enemy, a sortie. / (medicine) The outflow of a bodily fluid, particularly (now rare) in abnormal amounts.

To flow out, to proceed from, to come out or from. / To rush out, to sally forth. / To extend into, to open onto. / To turn out in a certain way, to result in.

(politics) Any issue, such as inflation or prices, that affects ordinary people in their daily lives.

(idiomatic) An issue or topic which is not of direct significance to a primary concern.