Initialism of Library of Congress.

(emergency medicine) Initialism of level of consciousness; also LoC. / (medicine) Initialism of loss of consciousness; also LoC. / (programming) Initialism of lines of code.

(informal, usually in the plural) A dreadlock.

Alternative letter-case form of LOC.

(software engineering, translation studies) Clipping of localization.

(slang) Clipping of loco (“crazy”).

Abbreviation of locative.

(dated, fandom slang) Correspondence, usually a letter, sent to a periodical commenting on either the contents of a previous issue or an earlier letter of comment.

(dated, fandom slang) To write a letter of comment to a periodical.

Alternative form of loc (“dreadlock”).