A Roman cognomen, notably borne by Lucius Annaeus Seneca, a Roman stoic philosopher, dramatist, and statesman.

A member of a tribe of Native Americans in western New York state.

The Iroquoian language of the Seneca people. / A city, the county seat of Nemaha County, Kansas / A town in Ontario County, New York.

plural of Seneca

A plant of the species Polygala senega

plural of Seneca root

One of 62 counties in New York, United States. County seat: Waterloo. / One of 88 counties in Ohio, United States. County seat: Tiffin.

(archaic) crude petroleum

(historical) A former village in Manhattan, New York City, New York County, New York State, United States; a settlement of freed slaves and other African Americans, also containing non-WASP European immigrants, demolished to make way for Central Park.

Of or relating to Seneca the Younger, Lucius Annaeus Seneca (ca. 4 BC–AD 65), Roman philosopher and statesman.