In low spirits from loss of hope or courage.

In a despondent manner.

One who desponds.

To give up the will, courage, or spirit; to become dejected, lose heart.

(archaic) Despondency.

The state of being downcast or despondent.

The loss of hope or confidence; despair or dejection. / A feeling of depression or disheartenment.

Third-person singular simple present indicative form of despond

present participle of despond

That causes despondency; disheartening.