(slang) A negative drug trip. / (slang) A drug that has depressant qualities. / (slang) Something or someone disagreeable, dispiriting or depressing; a killjoy. / A livestock animal that has collapsed.

(UK, slang, obsolete) A sixpence.

plural of downer

(Ulster) Donegal man

(informal, derogatory) A naysayer; one whose negative remarks depress or dissuade others.

plural of Debbie Downer

plural of Far-Downer

A worker or protester who participates in a sit-down.

plural of sit-downer