The room was filled with guffaws as the comedian delivered his punchline.

She guffaws at his jokes.

He let out a loud guffaw at the joke.

He couldn't help but guffaw at the comedian's hilarious joke.

He was guffawing at the comedian's jokes.

The room was filled with guffawing.

He guffawed at the joke.

The room was filled with guffawings as everyone found the joke hilarious.