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plica
noun
plica polonica
plicamycin
noun
(pharmacology)
An
antibiotic
C₅₂H₇₆O₂₄
with
antineoplastic
activity
which
is
produced
by
three
bacteria
of
the
genus
Streptomyces
(Streptomyces
argillaceus,
Streptomyces
tanashiensis,
and
Streptomyces
plicatus),
acts
by
inhibiting
DNA
transcription
and
replication,
and
is
administered
intravenously
especially
in
the
treatment
of
malignant
tumors
of
the
testes
or
in
the
treatment
of
hypercalcemia
and
hypercalciuria
associated
with
advanced
neoplastic
disease.
plication
noun
plicate
adj
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