(transitive) to lose (be unable to find) / (transitive, intransitive) to lose (not win) / (reflexive) to get lost

to be lost in it.

to lose consciousness, to pass out, to keel over, to faint

to lose heart, to give up hope

to lose patience, to lose one's patience

to get out of one's depth (to get in a body of water too deep for one to be able to touch the bottom)

to lose one's mind

(figuratively, idiomatic) to lose one's head, to take leave of one's senses, to lose one's mind

to waste time

to waste one's time