Clipping of ダウン症候群 (Daun shōkōgun, “Down syndrome”).

best

one's best [efforts]

vest

A lei; a Hawaiian garland / 霊: spirit; soul / 儷: companion, spouse, couple, pair / 冷: cool / 伶: lonely, solitary / 令: command, order / 麗: beauty, elegance / 例: precedent, example; regulation

碼: yard (three feet) / yard (outdoor space) / switchyard

going down, fall, decrease / being down with a disease, being unable to work due to sickness / being knocked down in boxing / a machine being down, failing to work

go down, fall, decrease / be down with a disease, be unable to work due to sickness / be knocked down in boxing / go down, malfunction

down (feathers)

inside; interior; inner portion