life / lifespan / lifetime / fate, destiny / (figuratively) the most important part or aspect of a thing

although

negative continuative form of かかわる

indifference to potential loss to life; recklessly dangerous

命: life

Alternative spelling of 拘る

involvement, relation

Alternative form of 関わり

to be in relation to, to be relevant to, to be involved in / to be involved in a negative way: to meddle, to interfere / to have a substantial effect on something, to endanger something

Alternative spelling of 拘る